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The Top 20 U.S. Cities with the Highest STD Rates

The Top 20 U.S. Cities with the Highest STD Rates

  • Explore the latest insights on STD rates and prevalence in top U.S. cities, along with efforts to address this public health concern.

Sexually transmitted diseases (STDs) continue to be a pressing public health concern across the United States. In this blog, we’ll delve into the top 20 cities grappling with high STD rates, shedding light on the challenges they face and the efforts being made to combat these infections.

1. Philadelphia, Pennsylvania
Philadelphia has recently taken the lead in STD rates, surpassing Memphis, Tennessee. With a staggering 2,004.2 cases per 100,000 people, it’s a city in urgent need of targeted interventions.

2. Memphis, Tennessee
While Memphis has slipped to second place, its STD rates remain alarmingly high. The city’s health authorities are working tirelessly to address this issue.

3. Jackson, Mississippi
Jackson, Mississippi, holds the third spot. Efforts to raise awareness, improve access to testing, and promote safe practices are crucial here.

4. Baltimore, Maryland
Baltimore faces significant challenges in tackling STDs. With 2,004.2 cases per 100,000 people, it’s essential to prioritize education and prevention.

5. New Orleans, Louisiana
The vibrant city of New Orleans grapples with high STD rates. Community outreach, education, and accessible healthcare services are vital.

6. Milwaukee, Wisconsin
Milwaukee’s STD rates demand attention. Collaborative efforts between healthcare providers, community organizations, and policymakers are essential.

7. Montgomery, Alabama
Montgomery, Alabama, ranks high in STD prevalence. Public health campaigns and targeted interventions can make a difference.

8. San Francisco, California
San Francisco, known for its progressive outlook, faces challenges in curbing STDs. Continued education and accessible testing are key. It has the third-highest STD rate in the nation, with 3,150 cases per 100,000 people1.

9. Augusta, Georgia
Augusta’s STD rates underscore the need for comprehensive sexual health programs. Empowering individuals with knowledge is critical.

10. St. Louis, Missouri
St. Louis grapples with high STD rates. Community clinics, outreach, and destigmatization efforts are essential.

11. Newark, New Jersey
Newark, New Jersey, is another city dealing with significant STD burden. Testing, treatment, and education are vital components of the response.

12. Columbia, South Carolina
Columbia faces challenges in reducing STD rates. Collaboration between healthcare providers, schools, and community organizations is crucial.

13. Little Rock, Arkansas
Little Rock’s efforts to combat STDs require sustained commitment. Raising awareness and promoting safe behaviors are essential.

14. Norfolk, Virginia
Norfolk’s STD rates emphasize the importance of accessible testing and education. Community health centers play a pivotal role.

15. Jacksonville, Florida
Jacksonville’s position in the top 20 highlights the need for targeted interventions. Public health campaigns can make a difference.

16. Atlanta, Georgia
Atlanta’s vibrant culture coexists with high STD rates. Comprehensive sexual health education and regular testing are essential.

See Also

17. Washington, D.C.
Our nation’s capital, Washington, D.C., also faces significant challenges in managing STDs. With a rate of 2,004.2 cases per 100,000 people, it’s crucial to prioritize prevention and accessible healthcare services.

18. Cleveland, Ohio
Cleveland faces challenges in reducing STD prevalence. Collaboration between healthcare providers and community organizations is key.

19. Richmond, Virginia
Richmond’s efforts to address STDs require a multifaceted approach. Empowering individuals with knowledge and resources is crucial.

20. Houston, Texas
Houston grapples with high STD rates. Culturally sensitive outreach and accessible clinics are essential components of the response.


These cities serve as a stark reminder that STD prevention and education remain critical. By working together, we can reduce the burden of these infections and promote healthier communities across the nation.

Note: Even if your city is not on this list, it does not mean that STDs do not exist there. These rankings can vary over time and may change based on various factors such as public health interventions, changes in population demographics, and reporting methodologies. For the most accurate and up-to-date information on STD rates by city, please refer to recent data from public health agencies or reputable sources.


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